Co-loaded lapatinib/PAB by ferritin nanoparticles eliminated ECM-detached cluster cells via modulating EGFR in triple-negative breast cancer

Abstract Cancer stem cell Accessories (CSC) cluster of triple-negative breast cancer (TNBC) is suggested to be responsible for therapy resistance, metastatic process and cancer recurrence, yet the sensitivity of CSC clusters of TNBC to ferroptosis remains elusive in a great measure.Current research revealed that epidermal growth factor receptor (EG

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Probabilistic Machine Learning for the Authentication of the Protected Designation of Origin of Greek Bottarga from Messolongi: A Generic Methodology to Cope with Very Small Number of Samples

Consumers are increasingly interested in the geographical origin Guitar Strings of foodstuff, as an important characteristic of food authenticity and quality.To assure the authenticity of the geographical origin, various methods have been proposed.Stable isotope analysis is a method that has been extensively used for products like wine, oil, and me

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Assessing the feasibility and effectiveness of household-pooled universal testing to control COVID-19 epidemics.

Outbreaks of SARS-CoV-2 are threatening the health care systems of several countries around the world.The initial control of SARS-CoV-2 epidemics relied on non-pharmaceutical interventions, such as social distancing, teleworking, mouth masks and contact tracing.However, as pre-symptomatic transmission remains an important driver of the epidemic, co

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